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Resident Evil 2 Remake: How to Open the Portable Safe

Resident Evil 2 Remake: How to Open the Portable Safe

Having trouble opening this little box? You haven’t been paying attention! Here’s how to open the Portable Safe and get the Spare Keys.
César Rebolledo · Published: 19 Jul 2026, 18:45

It looks like you're having quite a bit of trouble opening the Portable Safes in Resident Evil 2 Remake. They're one of the game's many puzzles, and solving them will help you obtain a couple of items, including a Hip Pouch.

What makes this puzzle unusual? Well, it basically has a random solution. So how are you supposed to open it? What's the trick? It's actually pretty easy. You simply need to make all the lights come on. Here's how it works.

How to Unlock the Portable Safe

Resident Evil 2 Remake - Portable Safe
  • The safe's dial is divided into 8 lights.
  • There are 8 buttons underneath it, each corresponding to one of the lights.
  • You need to turn on all the lights, one at a time, in counterclockwise order.
  • If you make a mistake, all the lights will go out, but each button will still correspond to the same light.
  • You can start wherever you like. It doesn't matter, as the button-to-light combinations change with every playthrough. Just keep trying different buttons.
  • If you're having trouble, you can write down which button corresponds to each light.

Remember that the two Portable Safes, whose locations change depending on whether you're playing the 1st Run or 2nd Run, contain the Spare Keys needed to open the lockers in the Safety Deposit Room. And don't forget that we have plenty of other solutions, tips, and secrets for you, including the locker combinations, the safe combinations, the locations of every weapon and all their upgrade parts, each character's Files, and, of course, the locations of every single Mr. Raccoon hidden throughout the game.

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