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Resident Evil Requiem Guide: Tips, Tricks and Secrets

Resident Evil Requiem Guide: Tips, Tricks and Secrets

Everything you need to know to complete Resident Evil Requiem 100%. Leon and Grace’s adventure will uncover secrets that were better left buried.
César Rebolledo · Updated: 11 Aug 2026, 13:11 · Published: 21 Jul 2026, 22:42

Welcome to our complete Resident Evil Requiem guide. Throughout these sections, we'll give you all the information you need to complete the game 100%. Our step-by-step walkthrough is designed to make sure you don't miss anything along the way, including collectibles, weapons and several secrets. It's also worth noting that this guide has been designed to avoid accidental spoilers. If you want to play through the game with us while avoiding spoilers, simply head to the first chapter and follow the walkthrough from there, without visiting any other sections unless necessary.

Bear in mind that sections containing potential spoilers are clearly marked. Don't go snooping around if you don't want to ruin any surprises.

Story

Resident Evil Requiem - Story section cover

The story of Resident Evil Requiem features two protagonists: Grace Ashcroft and the legendary Leon S. Kennedy. While Grace, an FBI agent, investigates a series of murders taking place across the country, Leon searches for answers about an illness that may be affecting far more people than it seems. This guide will show you how to complete every chapter and section 100% without missing anything along the way. This includes collectibles, weapons and much more.

Bear in mind that the menu has been designed to prevent accidental spoilers, but entering any of the chapters will reveal the name of its location.

Difficulty modes and differences

Resident Evil Requiem - Difficulty modes and differences section cover

As usual, Resident Evil Requiem gives you the option to play on several different difficulty modes. Aside from the usual overall changes to enemies and their behavior, there are a couple of major differences you should keep in mind before jumping into the game. It's best to know about them in advance and save yourself any nasty surprises.

Easter eggs

Resident Evil Requiem - Easter eggs section cover

To round out our complete Resident Evil Requiem guide, we've added a section featuring the best easter eggs we found while playing. You should probably avoid checking it out until you've finished the game. It's impossible to discuss some of these often well-hidden references without revealing spoilers.

Weapons

Resident Evil Requiem - Weapons section cover

Leon and Grace can use a wide variety of weapons in Resident Evil Requiem. Naturally, these are your main tools for getting rid of all the infected enemies and creatures standing in your way. This section of the guide explains how to obtain and upgrade every weapon, as well as covering postgame special weapons, infinite ammo and more. Bear in mind that this section contains unavoidable spoilers, so keep reading at your own risk.

Collectibles

Resident Evil Requiem - Collectibles section cover

Throughout the story of Resident Evil Requiem, you'll come across a large number of collectible items that can be picked up, completed or obtained. There are several different types, ranging from traditional collectibles to containers, locked cabinets and locks that can be opened with lockpicks. This section of the guide explains how to obtain all of them. Bear in mind that some location names may contain spoilers if you decide to take a look:

Puzzles

Resident Evil Requiem - Puzzles section cover

While completing the story of Resident Evil Requiem, you'll encounter a handful of puzzles and brain-teasers that must be solved to progress. There aren't many, but as usual, we'll give you the solution to every one of them in the following entries.

Safes

Resident Evil Requiem - Safes section cover

In Resident Evil Requiem, Grace can open several combination-locked safes. This mechanic has appeared in previous entries and requires you to find the exact numbers needed to open each safe, which contains a variety of items. This section of the guide explains where to find them and how to open them.

Endings

Resident Evil Requiem - Endings section cover

As with any game worth its salt, reaching the end of the story in Resident Evil Requiem will trigger a closing cutscene that brings the game to an end. However, unlike most entries in the series, Requiem has more than one ending. To clear up any confusion, we'll explain how to watch both of them.

The Final Puzzle

Resident Evil Requiem - The Final Puzzle section cover

Resident Evil Requiem features an entirely optional secret puzzle that requires you to complete a series of steps in different locations throughout the story. It appears in the Challenges section as "The Final Puzzle". Completing this challenge rewards you with 20,000 points to unlock Extra Content, but solving it won't be easy.

Spoiler warning: you shouldn't read this section before completing your first playthrough. Explaining this puzzle involves unavoidable spoilers.

Frequently asked questions

In this section of the guide, you'll find the most common frequently asked questions about Resident Evil 9 Requiem, along with their answers, so you can clear up any doubts you may have about the latest entry in Capcom's popular franchise:

  • PC requirements: these are the minimum and recommended system requirements for playing on PC.
  • Editions: find out which editions of the game are available and what content each one includes.

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