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Resident Evil 4 Remake Guide and Walkthrough: Tips, Tricks and Secrets

Resident Evil 4 Remake Guide and Walkthrough: Tips, Tricks and Secrets

Complete Leon’s adventure in Spain with our comprehensive guide. Find everything you need to get 100%, including the story, collectibles, weapons, tips and much more.
César Rebolledo · Updated: 13 Aug 2026, 13:18 · Published: 20 Jul 2026, 00:22

Welcome to our Resident Evil 4 Remake guide. This modern reimagining updates the classic originally released on GameCube and subsequently remastered for a huge variety of platforms. Throughout this guide, we'll explain how to complete 100% of the game, including a story-spoiler-free walkthrough, every treasure and weapon, and much more.

Story

Resident Evil 4 Remake - Story

The story of Resident Evil 4 Remake takes Leon, a survivor of Raccoon City, to a remote village in Spain in search of the U.S. President's daughter. In this guide, we'll show you how to beat the game without any story spoilers while completing 100% of its activities, puzzles and collectibles.

Weapons

Resident Evil 4 Remake - Weapons

There are plenty of weapons that you can buy from the Merchant or obtain in other ways. Each one has its own unique features, so we'll explain how to get them all and break down their stats to help you choose the best weapons for your playstyle.

S+ Rank

Resident Evil 4 Remake - S+ Rank

The S+ Rank challenge is back. In this section, you'll find the requirements and rewards for earning an S+ Rank on every difficulty, along with tips and tricks for getting S+ on Hardcore.

Collectibles

Resident Evil 4 Remake - Collectibles

There are more than one hundred collectibles to find as you play. Each type has its own unique features and can earn you special rewards. Here, we'll show you how to find them all and explain what you'll get for collecting them.

  • Clockwork Castellans: destroy all 16 figures to unlock a special weapon.
  • Small Keys and locked drawers: there are 8 keys and drawers in total, with extra treasures waiting inside.
  • Special keys and chests: there are 10 special chests scattered throughout the game that require 2 special keys. Inside, you'll find more treasures to sell to the Merchant.
  • Blue Medallions: one of the original game's classic collectibles is back. Here, you'll learn where to find all 6 groups of medallions you need to destroy in exchange for Spinels.
  • Treasures: the game's main collectible. With our help, you can find more than 100 treasures to sell for money.

Puzzles

Resident Evil 4 Remake - Puzzles

You'll encounter a huge number of puzzles to solve, most of which are mandatory. Although they all have logical solutions, this section provides the solution for every difficulty, as some puzzles must be solved differently when playing on the highest difficulty settings.

Skips

Resident Evil 4 Remake - Best skips

Skips are shortcuts that can save you time, sometimes allowing you to bypass entire sections of the game and shave several minutes off your run. They're particularly useful for speedruns, and Resident Evil 4 Remake has quite a few of them. Here, we'll cover the best skips currently known, excluding glitches that are likely to be patched out before long.

Enemies and bosses

Resident Evil 4 Remake - Enemies and bosses

Leon will have to face a whole host of enemies and bosses during his adventure. In this handy enemy encyclopedia, we'll explain how to defeat every single one of them, including the major bosses:

Requests

Resident Evil 4 Remake - Requests

Requests are the game's side quests. In this section, you'll learn where and how to complete every one of them so that you can earn items to trade with the Merchant for special gear.

Shooting Ranges

Resident Evil 4 Remake - Shooting Ranges

The Shooting Ranges let you put your aim to the test and earn Gold and Silver Tokens. These can be exchanged for Charms, accessories that grant special effects. Here, you'll learn where to find every Shooting Range and how to earn its best rewards.

Frequently Asked Questions

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