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Organ Transport Box Puzzle Solution in Resident Evil Requiem

Organ Transport Box Puzzle Solution in Resident Evil Requiem

Here’s how to solve the Organ Transport Box puzzle in Resident Evil Requiem. A strange box in the garage may be hiding something important.
César Rebolledo · Published: 21 Jul 2026, 22:58

Throughout the story of Resident Evil Requiem, you'll have to solve several puzzles to progress or earn additional rewards. We're not talking about finding item X to open lock Y, but rather proper, old-school puzzles whose solutions may either change or remain the same depending on the circumstances. In this case, we'll explain how to solve the Organ Transport Box puzzle, which you'll encounter during Patient Center (III).

Where is the Organ Transport Box puzzle?

To solve this puzzle, you'll need to reach the Garage in the southwestern corner of the Patient Center's ground floor. You can reach this area by heading past the Janitor's Office. The hallway leading there can be accessed through the Level 1 security door in the southwestern corner of the ground floor. You'll obtain the ID wristband needed to open it as part of the story. Once inside the Garage, head to the southwestern section shown below.

Resident Evil Requiem - Organ Transport Box puzzle, box location

You'll see the Organ Transport Box sitting on the open bed of a truck. Mist is pouring out of it, so you can't miss it.

Organ Transport Box puzzle solution

Once you have the box, examine it and turn it over. You'll be able to remove a panel, giving you access to the box's locking mechanism. The solution can be found in the Unlocking the Organ Transport Box document. If you're having trouble making sense of it, use the image below as a reference and follow these instructions:

Resident Evil Requiem - Organ Transport Box puzzle, locking mechanism interface with solution instructions
  • 1: turn the dial until it points to "HAND".
  • 2: move the switch up to the middle line.
  • 3: the switch marked "5" must be down.
  • 4: the switch marked "2" must be down.
  • 5: turn the dial until it points to "AUTO".

If you've done everything correctly, the box will open and you'll receive the Artificial Lungs, which can be used on the Organless Corpse in the Examination Room.

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