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Patient Center (IV) 100% Walkthrough in Resident Evil Requiem

Patient Center (IV) 100% Walkthrough in Resident Evil Requiem

Here's what you need to do to complete Patient Center (IV), the sixth chapter of Resident Evil Requiem. Leon returns to interrogate the deranged scientist.
César Rebolledo · Published: 11 Aug 2026, 18:10

Care Center (IV) is the sixth chapter or sixth part of the story of Resident Evil Requiem. It begins after jumping through the hole in the Security Manager's Office at the end of Grace's section. As usual, throughout this walkthrough we will provide directions to help you complete as much of the game as possible, avoiding spoilers wherever possible while ensuring that you obtain all collectibles, receive help with puzzles and more.

Find Victor's office

Follow the only available path, climbing the stairs to the northeast. Look out for a crate you can break just before going through a door. On the other side, you will see a Green Herb on a table. Immediately afterwards, move forward and look to the left. You will find an alcove containing a couple of desks.

Resident Evil Requiem - Care Center (IV), location of the Satiety Suppression Medical Records in the southeastern corner of the Attic

On one of them, you will find the Satiety Suppression Medical Records file. After collecting it, look to the opposite side and move a piece of furniture so that you can squeeze through the gap. Carefully search the area as you move forward to collect some ammunition. The map shows some shotgun shells in the corner, but they cannot be picked up. The shells on the northern side, however, can. When you hear a noise, crouch and round the corner.

Resident Evil Requiem - Care Center (IV), Chunk in the Attic shortly after you begin playing as Leon

Yes, it is another Chunk like the one Grace encountered. Approach carefully without standing up to collect the MSBG 500, a shotgun, from the floor.

Resident Evil Requiem - Weapons, Leon's MSBG 500 in the inventory

The Chunk will come after you as soon as you pick it up. Blast it directly in the face. It will stagger with each hit, and after the third or fourth shot it will fall, allowing you to perform a finishing move with the axe. Make it follow you east, towards the shotgun ammunition icon.

Resident Evil Requiem - Care Center (IV), shotgun ammunition icon in the southeastern corner of the Care Center Attic

As it comes after you, it will break the obstacle immediately to the left of the icon on the map, revealing a ladder you can climb. If it does not break it on the first attempt, repeat the process and lure it towards you until the scaffolding collapses. Distract it so that you can climb the ladder. You will find more shotgun ammunition and can also shoot it in the face when it tries to climb up. This will give you another opportunity to perform a critical attack on its face. Right in its face, naturally.

Resident Evil Requiem - Care Center (IV), Leon prepares a critical attack from the top of the scaffolding in the Attic

Keep an eye on the map, as the Chunk will break sections of the walls, revealing more items in the northern area, including an Injection and additional shotgun ammunition. When it starts crawling, run around in circles until it stands up again, then continue shooting it in the face and performing finishing moves until it dies. You can collect a couple of Hand Grenades from its remains.

Resident Evil Requiem - Weapons, Leon's Hand Grenade

If you do not want to miss anything, open the Crafting menu and make a Double Hand Grenade. There is an achievement/trophy that requires you to craft every possible item with Leon. Make sure to search the northwestern corner for more ammunition before opening the door and continuing through another hallway. Immediately after going through, you will find your first cabinet with a broken lock. You will probably remember seeing several of them while playing as Grace, and they should be marked on your map. Leon can force them open to retrieve the items inside.

Resident Evil Requiem - Care Center (IV), cabinet with a broken lock in the Attic

This one contains a Compensator for the Alligator Snapper and the Basement Safe Code file. Afterwards, follow the only available path, collecting any resources you find along the way, until you reach a switch that lowers a ladder.

You will emerge in the Chairman's Office, on the second floor of the Care Center's West Wing.

Resident Evil Requiem - Care Center (IV), Leon's location after descending from the Care Center Attic

As you can probably imagine, it is time to take a substantial detour to open those cabinets. Bear in mind that there will not be many major changes in previously explored areas, although you will encounter more Mutant Heads. Remember that you can attack any enemy from behind with the axe to kill it instantly. In most cases, you will destroy its head, preventing it from transforming later. If an enemy spots you, shoot it twice in one leg, perform a melee attack to send it crashing into a wall and then finish it off with the axe.

Resident Evil Requiem - Care Center (IV), Leon finishes off an enemy with the axe

Here are the cabinets you need to open:

  • On the second floor:
    • Gallery Cabinet (head west along the hallway from your starting position. It contains ammunition and the Dishwasher's Note).
    • Records Room Cabinet (in the southwestern section of the second floor. You will obtain resources and find a Mr. Raccoon). Note: save the Mixed Herb (G+G) until you obtain a third herb, then combine them to create a (G+G+G) for the achievement/trophy tied to crafting items with Leon.
  • On the ground floor:

From the last cabinet, climb the northwestern stairs to the third floor. You can now open the Warped Door. Be careful, as there is a zombie carrying an explosive just before the door.

Resident Evil Requiem - Care Center (IV), location of the Warped Door in the northwestern section of the third floor

Search Victor's office

After going through the door, you will encounter... something bad. Search the Break Room. It will not be long before a Mutant Head appears. Eliminate it and keep an eye on the double doors in the southeastern corner: throw the Double Hand Grenade as soon as they open to eliminate two Mutant Heads at once.

Resident Evil Requiem - Care Center (IV), double doors through which two Mutant Heads enter the Break Room

Once you have eliminated all three Mutant Heads, proceed to the Meeting Room, where you will find a vase containing ammunition, and then enter the Director's Office. You will find an Injection, a Hand Grenade and a painting on the eastern wall that you can interact with. Activating it will cause more zombies and Mutant Heads to appear, so retreat quickly to avoid becoming trapped here with no room to manoeuvre. There is a fire axe in the Meeting Room that you can throw to stun enemies before finishing them off with your own axe. There will be another zombie carrying an axe in the next room. You will face two Mutant Heads in total, so take advantage of the axes: throw them at the creatures and then use your own axe's finishing move to eliminate the threat quickly.

Follow the newly opened path through the office to the Elevator. One thing will lead to another and we will return to Grace.

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