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Resident Evil 3 Remake: ALL Key Items and Keys

Resident Evil 3 Remake: ALL Key Items and Keys

Find out where and how to obtain every key item in Resident Evil 3 Remake and what each one is used for. Bear in mind that a few of them will change location depending on the difficulty setting.
César Rebolledo · Updated: 13 Aug 2026, 09:51 · Published: 13 Aug 2026, 09:04

In addition to collectibles, Resident Evil 3 Remake, like any action-adventure game, sometimes requires us to find key items. These may be keys, objects used to restore power, or devices needed to complete a particular puzzle. Almost all of them are required to progress, while some also have optional uses beyond what is needed to continue the story. To make sure you don't have any trouble finding them, this guide explains where to obtain every key item and where each one can be used.

Downtown

You will find 7 key items while exploring Downtown:

Fancy Box and Red Jewel

Resident Evil 3 Remake - Key items: Fancy Box and Red Jewel

  • Where is it? In the kitchen inside Moon's Donuts.

  • What is it used for? Examine the Fancy Box to obtain the Red Jewel. It is used in the jewel puzzle.

Fire Hose

Resident Evil 3 Remake - Key items: Fire Hose

  • Where is it? In the hallway inside Kite Bros. Railway.

  • What is it used for? It is used to extinguish the fire in the alley off the main street, allowing you to progress.

Bolt Cutters

Resident Evil 3 Remake - Key items: Bolt Cutters

  • Where are they? Hanging on the wall inside the safe room you reach after using the Fire Hose.

  • What are they used for? They are used to open the door in the safe room where you obtain them, the Supermarket door on Redstone Street, the chained gate in the alley behind Moon's Donuts, and the display case containing the Shotgun inside Kite Bros. Railway.

Fancy Box and Blue Jewel

Resident Evil 3 Remake - Key items: Fancy Box and Blue Jewel

  • Where is it? Inside the Supermarket, the building on the western side of Redstone Street's main road. You need the Bolt Cutters to open its door. In Nightmare Mode, it is located in the alley behind Moon's Donuts, which also requires the Bolt Cutters to access.

  • What is it used for? Examine the Fancy Box to obtain the Blue Jewel. It is used in the jewel puzzle.

Lock Pick

Resident Evil 3 Remake - Key items: Lock Pick

  • Where is it? Inside the substation, down the stairs beyond the safe room. It is obtained from the corpse in the corner.

  • What is it used for? The item you initially collect is a Case. Examine it to obtain the Lock Pick. It is required to open two doors needed to progress and can also be used to open locked cases and lockers.

Fancy Box and Green Jewel

Resident Evil 3 Remake - Key items: Fancy Box and Green Jewel

  • Where is it? Inside the toy store on Redstone Street. You need the Lock Pick to open the door. In Nightmare Mode, it is located inside Redstone Pharmacy.

  • What is it used for? Examine the Fancy Box to obtain the Green Jewel. It is used in the jewel puzzle.

Sewers and Demolition Site

While exploring the Sewers and Demolition Site, you will find a total of 2 key items.

Battery Pack

Resident Evil 3 Remake - Key items: Battery Pack

  • Where is it? On a table inside the Laboratory.

  • What is it used for? It opens the locked doors inside the Sewers. The Battery Pack can be inserted and removed as needed.

Kendo's Gate Key

Resident Evil 3 Remake - Key items: Kendo's Gate Key

  • Where is it? Inside Gun Shop Kendo, in the key cabinet immediately after speaking to Kendo.

  • What is it used for? It opens the alley gate beside the store.

Police Station

While exploring the Police Station, you should find a total of 5 key items.

ID Card


  • Where is it? At the Police Station Entrance. Kill zombie Brad and take it from his body. In Nightmare Mode, it is inside the small room at the bottom of the stairs near the entrance, before entering the Police Station.

  • What is it used for? It opens the locked cases inside the Police Station.

Safety Deposit Room Key

Resident Evil 3 Remake - Key items: Safety Deposit Room Key

  • Where is it? On top of some boxes on the third floor. This is the only room you can explore on the entire third floor, so it is difficult to miss.

  • What is it used for? It opens the Safety Deposit Room on the ground floor.

Battery

Resident Evil 3 Remake - Key items: Battery

Where is it? Inside the Safety Deposit Room. You obtain it by solving the Safety Deposit Room keypad puzzle.
What is it used for? Combine it with the Electronic Gadget to create the Detonator.

Electronic Gadget

Resident Evil 3 Remake - Key items: Electronic Gadget
  • Where is it? On the Shower Room wall on the second floor.
  • What is it used for? Combine it with the Battery to create the Detonator.

Detonator


  • Where is it? It is obtained by combining the Electronic Gadget with the Battery.

  • What is it used for? It is attached to the explosives on the Shower Room wall on the second floor.

Hospital (Carlos)

While playing through the Hospital section as Carlos, you will find a total of 7 key items:

Tape Player

Resident Evil 3 Remake - Key items: Tape Player

  • Where is it? Inside Laboratory Reception. You must pass through this area because it is the only available route.

  • What is it used for? Combine it with the Audiocassette Tape to create the Tape Player (Tape Inserted).

Locker Room Key

Resident Evil 3 Remake - Key items: Locker Room Key

  • Where is it? In the Courtyard. To reach it, go up to the second floor and jump through the window beside the Linen Room door.

  • What is it used for? It opens the Locker Room door on the second floor.

Hospital ID Card

Resident Evil 3 Remake - Key items: Hospital ID Card

  • Where is it? Inside a locker accessed through the Staff Room on the second floor.

  • What is it used for? It opens the card-locked door inside the Nurses' Station on the second floor and the Operating Room door on the first floor.

Audiocassette Tape

Resident Evil 3 Remake - Key items: Audiocassette Tape

  • Where is it? Inside the Treatment Room on the second floor. You reach it by unlocking the Nurses' Station door with the Hospital ID Card.

  • What is it used for? Combine it with the Tape Player to obtain the Tape Player (Tape Inserted).

Tape Player (Tape Inserted)


  • Where is it? It is obtained by combining the Tape Player with the Audiocassette Tape.

  • What is it used for? It opens the voice-locked door inside Laboratory Reception on the first floor.

Vaccine Sample

Resident Evil 3 Remake - Key items: Vaccine Sample

  • Where is it? Inside Nathaniel Bard's laboratory, which you reach after using the Tape Player (Tape Inserted).

  • What is it used for? Use it on Jill in the room where she is resting to progress.

Detonator

Resident Evil 3 Remake - Key items: Detonator

  • Where is it? Inside one of the crates in the lobby during the siege.

  • What is it used for? When Tyrell tells you to, attach it to the explosives to end the zombie assault.

Hospital Underground

While pursuing a certain character through the Hospital Underground, you will need to find one key item that is actually three identical items:

Fuse


  • Where is it? There are three scattered throughout the Underground Storage. Check the Underground Storage Fuse puzzle for more details.

  • What is it used for? The Fuses restore power to the elevator leading to the Surveillance Room.

NEST 2

In NEST 2, the final area in the game, you will find a total of 5 key items.

Override Key

Resident Evil 3 Remake - Key items: Override Key

  • Where is it? Inside the vaccine synthesis room. Interact with the security device in the northeastern corner.

  • What is it used for? It opens the locked door in the lower-floor hallway.

Adjuvant Sample

Resident Evil 3 Remake - Key items: Adjuvant Sample

  • Where is it? Inside the Incubation Lab. Use the Override Key and go down the stairs in the room it unlocks to reach this area.

  • What is it used for? Combine it with the Antigen Sample to obtain the Vaccine Base.

Antigen Sample

Resident Evil 3 Remake - Key items: Antigen Sample

  • Where is it? Inside Lab 1. Go up the stairs in the room opened with the Override Key, located in the hallway near the safe room.

  • What is it used for? Combine it with the Adjuvant Sample to obtain the Vaccine Base.

Vaccine Base


  • Where is it? It is obtained by combining the Adjuvant Sample with the Antigen Sample.

  • What is it used for? Insert it into the machine on NEST 2's upper floor, inside the western room, to begin the vaccine synthesis puzzle.

Vaccine


  • Where is it? It is obtained by completing the vaccine synthesis puzzle.

  • What is it used for? It serves a story-related purpose and does not need to be used manually.

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