
Among all the Reagents available in Hades 2, Entropy is undoubtedly one of the most special resources in the game. This item is required to perform the Cauldron Incantation known as "Dissolution of Time", which allows you to put an end to Chronos' ability to reconstitute himself night after night. If you have made it this far, you probably want to know how to obtain Entropy but are not quite sure what to do. If so, keep reading this section of our guide, as we explain everything you need to know below.
The only way to obtain Entropy in Hades 2 is by permanently defeating the final boss Typhon, the final boss of the surface route. Be warned, simply defeating Typhon in a regular battle will not work, as this only rewards you with a Void Lens. You need to eradicate him completely by first performing the "Disintegration of Monstrosity" Incantation at the Cauldron.
So, how is this done? This task is actually part of the sequence of steps required to unlock the game's true ending. You can find all the details at the linked page, but here is a brief summary of what you need to do:
After performing this Incantation, you can embark on another run across the surface. This time, when you fight and defeat Typhon, Melinoë will use the Gigaros spear at the end of the battle to kill him permanently. The boss will drop a Void Lens as usual, as well as the long-awaited Entropy Reagent.
And that's it: you now know how to obtain Entropy. With it in your inventory, you can finally perform the "Dissolution of Time" Incantation and put an end to Chronos' evil deeds.